URICANORM TABLET

Each tablet contains:

Mass extract derived from: Guduchi 500mg, Triphala 300mg, Ashwagandha 200mg, Punarnava 200mg, Sariva 200mg

Powders of: Shudh guggulu 100mg, Shudh shilajit 75mg, Musta 45mg, Guduchi 45mg, Erandmool 45mg, Vidang 45mg, Trivrit 45mg, Dalchini 25mg, Sonth 25mg, Marich 20mg, Pippali 20mg

Guduchi (Tinospora cordifolia)

Guduchi is a well-known rasayana drug with tridoshar properties therefore it helps in pacification of vitiated dosha. In a clinical study it was observed that Guduchikwatha was found very effective in Vatarakta due to its Rasayana (anti-oxidant), vaysthapan (anti-ageing), vatahara, ushna guna (hot in potency) and steroidal properties. ^{AyurpharmInt J Ayur Alli Sci., Vol. 4, No. 11 (2015) Pages 206 – 213}

Another study showed that the aqueous extract of Tinospora cordifolia (AETC) has significant analgesic and anti-inflammatory activities.^{International Journal of Basic Medical Science - November 2011, Vol: 2, Issue: 5}

Ashwagandha (Withania somnifera)

Ashwagandha is a Rasayana drug and it provides strength to the body and helps to balance vata dosha the causative factor of hyperuricemia. According to a research study, the suppressive effect of Withania somnifera root powder on gouty arthritis was observed. It also showed potent analgesic and antipyretic effect with the absence of gastric damage at different dose levels. The above results associate the anti-arthritic, analgesic and antipyretic actions of W. somnifera root powder with absence of gastric damage. ^{Chemico-Biological Interactions 164 (2006) 174–180}

Guggulu (Commiphora mukul)

In Ayurvedic texts Guggulu is a well-known drug mentioned to be used in sandhishool (Joint pain) due to its vednasthapan (Analgesic) properties which helps to relief pain in the joints.The result of several studies also confirms anti-inflammatory and anti-arthritic activities of guggulu.

Triphala (Classical formulation)

Triphala has anti-inflammatory effects and helps in healing process, it provides nutrients which strengthen bones and detoxify toxins (uric acid) which may cause inflammation. Therefore, Triphala provides great relief in gout, arthritis and other problems related to joint pain.

In a study, an experimental model for gouty arthritis was treated with Triphala. The results obtained from the study clearly indicated that Triphala exerted a strong anti-inflammatory effect against gouty arthritis.^{Vascular Pharmacology 48 (2008) 14–20}

Musta (Cyperus rotundus)

Musta is used in Vatajvikar (vata disorders). In a study, the extract of Musta possessed anti-inflammatory activity against carrageenan induced oedema and also found effective against formaldehyde induced arthritis in albino rats. It also possesses analgesic activity.

Shilajit (Asphaltum punjabianum)

Shilajit has analgesic and anti-inflammatory effects and is thus useful for different painful conditions of the body. Shilajit is also found to be very beneficial in rheumatoid arthritis, osteoarthritis, and gout.

Erandmool (Ricinus communis)

It balances Vata and Kapha dosha. Therefore, it is effective in treating vata related disorders. The extract of the root was studied for anti-inflammatory activity in carrageenan induced hind paw edema model in which R. communis roots showed anti-inflammatory activity against carrageenan induced paw edema.^{Int.J.PharmTech Res.2013,5(3)}

Vidang (Embelia ribes)

Embelia ribes possess wide range of medicinal properties due to its vatahar properties. It also has analgesic and antioxidant properties that help to provide relief from pain.

Dalchini (Cinnamomum zeylanicum)

Dalchini has kaphavatahar properties that help in balancing the increased vata dosh. In an experimental study administration of cinnamomum extract significantly reduced the elevation of uric acid in urine.^{Pol. J. Food Nutr. Sci. 2008, Vol. 58, No. 3, pp. 389-395}

Sonth (Zingiber officinale)

Sonth has vata balancing properties and it also effective in relieving pain. Therefore, Sonth can be used in case of hyperuricemia. A study also revealed that Ginger flavonoids are able to reduce uric acid levels in hyperuricemic rats with no effects on the level of this biological metabolite in normal animals and prevent oxidative stress. ^{International Journal of Advanced Research (2015), Volume 3, Issue 10 , 1033 – 1039}

Marich (Piper nigrum) and Pippali (Piper longum)

Pippali and Marich works as a detoxifier of amadosh (toxins) and also act as yogvahi (Increase bioavailability of the other herbs). They also possess sothahar (Anti-inflammatory) properties by virtue of which they are helpful in conditions like hyperuricemia.

According to a study,the anti-inflammatory effect of piperine was investigated on an experimental model for gouty arthritis and the study clearly indicated that piperine inhibit the monosodium urate crystal induced inflammation and can be regarded as therapeutic drug for the treatment of acute gouty arthritis^{. Piperine Inhibits Gouty Arthritis. Inflammation, Vol. 34, No. 3, June 2011}

Punarnava (Boerhavia diffusa)

Punarnava is a plant of rasayana category drug. Studies approving anti-inflammatory action along with diuretic properties have been observed by various authors. The anti-inflammatory action of Punarnava helps to reduce the inflammation in the joints.The extracts of the roots of B.diffusa showed significant anti-inflammatory activity and anti-arthritis in albino rats. ^{Asian J. Applied Sci.4 (7):663- 684, 2011}

In another study author found significant diuretic activity of Punarnava root extract in which he observed 90.3% increase in the volume of urine with the extract whereas extract of leaves and flower showed 67.22% increase in the volume of urine. Through its diuretic effect it increases the uric acid excretion and hence lowering blood serum levels of uric acid. ^{PlantaMedica, vol 28, no 1, pp 62-66, 1975.}

Sariva (Hemidesmus indicus)

Sariva has kaphavatahar properties so it is utilized in Gout. In a study, the protective effects of Hemidesmus indicus on arthritis models were seen. The fraction of H. indicus showed significantly higher anti-arthritic activity.^{Asian Pacific Journal of Tropical Medicine (2012)130-135}

Trivrit (Operculina turpethum)

In Ayurveda the roots of Trivrit are used in Rheumatism and in painful conditions. In a study, the anti-inflammatory potential of different extracts of O. turpethum has been reported in arthritis model. The aqueous extract was reported more potent fraction in all three animal models. ^{Journal of Pharmacognosy and Phytochemistry 2017; 6(1): 23-26}

Hyperuricemia is the presence of excess uric acid in the blood. High levels of uric acid may lead to attacks of gout or the development of kidney stones if it is not regulated on time.

Uricanorm tablets are prepared from the combination of potent herbs and minerals which are highly beneficial in conditions like hyperuricemia and gout. It is a blend of anti-inflammatory, analgesic, and anti-hyperuricemic drugs.

• Ingredients such as Guggulu, Musta, Shilajit, Erandmool and Trivrit helps in decreasing the inflammation.
• Guduchi, Ashwagandha, Sariva and Dalchini provide anti-gout action.
• Triphala, Sonth, Marich and Pipali helps in controlling Uric acid levels.
• Punarnva as a diuretic helps in removal of uric acid out of the body through urine.

These drugs in combination help to normalize the levels of uric acid, prevent the inflammation and pain in the joints. It also works as a rejuvenating and anti-oxidant to defy free radicals. Therefore, Uricanorm tablet helps to prevent the gouty arthritis.