ORNAZYME

ENZYMES

Enzymes are biological catalysts. They catalyse the chemical reactions that happen inside living things i.e. they are involved in biological chemical reactions. They are the “gnomes” inside each one of us that take molecules like nucleotides and align them together to create DNA, or amino acids to make proteins, and they perform thousands of such functions. Therefore, they are essential for respiration, digesting food, muscle and nerve function, among thousands of other roles.

Enzyme activity can be affected by a variety of factors, such as temperature, pH and concentration. Enzymes work best within specific temperature, pH ranges and sub-optimal conditions can cause an enzyme to lose its ability to bind to a substrate.

  • Temperature: Raising temperature generally speeds up a reaction, and lowering temperature slows down a reaction. However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working.
  • pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.
  • Enzyme concentration: Increasing enzyme concentration will speed up the reaction, as long as there is substrate available to bind. Once all of the substrate is bound, the reaction will no longer speed up, since there will be nothing for additional enzymes to bind to.
  • Substrate concentration: Increasing substrate concentration also increases the rate of reaction to a certain point. Once all of the enzymes have bound, any substrate increase will have no effect on the rate of reaction, as the available enzymes will be saturated and working at their maximum rate.

Some enzymes cannot function unless they have a specific non-protein molecule attached to them. These are called cofactors. For instance, carbonic anhydrase, an enzyme that helps maintain the pH of the body, cannot function unless it is attached to a zinc ion.

SOME FUNCTIONS OF ENZYME

The chemical reactions that keep us alive – our metabolism – rely on the work that enzymes carry out.

The digestive system – enzymes help the body break down larger complex molecules into smaller molecules, such as glucose, so that the body can use them as fuel.

DNA replication – each cell in your body contains DNA. Each time a cell divides, that DNA needs to be copied. Enzymes help in this process by unwinding the DNA coils and copying the information.

Liver enzymes – the liver breaks down toxins in the body. To do this, it uses a range of enzymes.

WHY THERE IS A NEED OF ENZYMES?

Most of the persons have digestive concerns. These digestive concerns may be raised from insufficient secretion of enzymes. To overcome these digestion problems people, opt for supplementation of enzymes. Problems with liver, stomach and pancreas etc can also reduce the number of important enzymes that a body produce. Therefore, a person may not get enough enzymes to thoroughly digest food and obtain all the nutritional value.

According to Ayurveda, balanced agni (digestive fire) is at the root of Health. According to Acharaya Charak (the father of Ayurvedic medicine) “Longevity, complexion, strength, health, muscle mass, lustre, immunity, energy all these depends on agni. One dies if this agni get extinguishes. If this agni is in balance one lives long life free from any disorders and if this agni gets deranged a person get various disorders. Hence, agni is at the root cause of all.

Rather than consuming digestive enzymes, it is more effective to balance the imbalanced agni (digestive fire) to restore the proper digestion. Here digestive fire is correlated to gastric juices and different enzymes at gastrointestinal level. Along with balancing of agni the health of specific organs that secrets enzymes should also be maintained.

Each 5 ml of syrup contains:

Aqueous extract derived from: Amaltas 100mg, Kakmachi 100mg, Bhringraj 100mg, Punarnava 100mg, Kasni 50mg, Bhumiamalaki 50mg, Rohitak 50mg, Haritaki 50mg, Ajwain 50mg, Kutaki 5mg

Powder of: Sanidhav Lavan 5mg

Kutaki (Picrorhiza kurroa)

It is an established herbal remedy for variety of disease ranging from indigestion to hepatitis. Kutaki helps to maintain proper functioning of Liver and stomach. It also helps to balance the agni so that indigestion can be cured.

Modern clinical studies have confirmed the efficacy and safety of Picrorhiza kurroa for the treatment of liver disease. Pharmacologically, Kutkin (Picrosides and kutkosides) has hepatoproptective activity.

Ajwain (Trachyspermum ammi)

Ajwain helps to manage digestive problems by promoting digestive fire due to its deepan action (appetizer). Thymol is the main constituent in ajwain which soothes the secretion of gastric juices and improves digestion. It is a potent carminative and antispasmodic. It also helps in regulating bowel movements and removes constipation.

Sendha Namak (Rock salt)

It is Vibandhaghna, means it relieves constipation and bloating. It also improves appetite, removes intestinal and abdominal gases, cramps and soothes heartburn.

Haritaki (Terminalia chebula)        

It will digest the undigested food residues by inducing or restoring normal peristaltic movement of the intestine by governing vata. Haritaki is a natural laxative and contains dietary fibres, which fights constipation. It also prevents formation of gas or helps in expulsion of formed gas by combating flatulence.

Kasani (Cichorium intybus)

Kasni has ushna (hot) and laghu (light) in nature due to which it is used to aid digestion and promote appetite. Kasni is also effective in promoting liver functions. A study results ascertain that C. intybus possess significant hepatoprotective activity against CCl4- induced hepatotoxicity. There were significant changes in serum biochemical parameters such as ALT, AST, ALP, bilirubin, albumin, total protein, and γ -glutamyl transferase (GGT) in carbon tetrachloride intoxicated rats, which were restored towards normal values in C. intybus treated animals.

Bhringraj (Eclipta alba)

Bhringraj increases the production of bile from liver, improves liver functions, reduces constipation and corrects digestion and enhances metabolism. The components of E. alba helps to reduce fat deposition and stimulates hepatocyte regeneration in the liver.

The study for hepatoprotective action of hydro alcoholic extract of whole plant of E. alba has been conducted at subcellular levels in rats. The restoration of loss of hepatic lysosomal acid phosphatase and alkaline phosphatase by CCl4 was significantly restored by Bhangra.

Rohitak (Tecomella undulate)

It has been used in the indigenous systems of medicine for liver, spleen and abdominal complaints. As a hepatoprotective T. undulata potentially effective in blunting lipid peroxidation, suggesting that the extract possibly has antioxidant property to reduce ethanol-induced membrane lipid peroxidation.

Bhumiamlaki (Phyllanthus niruri)

In Ayurvedic literature, Bhumiamlaki is known to be used as Kaphapittahara (Balances kapha and pitta) and Kaamalahar (Which cures jaundice). It provides hepatoprotective action as it normalizes Reactive Oxygen Species by their high antioxidant content and attenuating endogenous antioxidant enzymes to their normal level and stimulates the liver repair mechanism.

Punarnava (Boerhavia diffusa)

In Ayurveda, Punarnava is known to be used as Mootrala (diuretic), Sothaghna (anti-inflammatory), and Rasayana (rejuvenator). It has a pittahar action. Punarnava works as tonic, provides nourishment to the body by clearing toxins from all body channels. It also has proved studies which show hepatoprotective action of Punarnava. The studies have shown the following positive responses in the treatment of liver diseases-

  • Elevation in the decreased levels of antioxidant enzymes i.e. Superoxide dismutase (SOD), catalase (CAT), Glutathione peroxidase (GPx) and Glutathione-S-transferase (GST).
  • Elevated levels of liver marker enzymes ALT, AST, ALP and Bilirubin were restored near to normal

Amaltas (Cassia fistula)

It has ability to subside various stomach ailments such as gas, flatulence and acidity. It reduces the colic pain and therefore, helps in proper digestion of food.

Kakmachi (Solanum nigrum)

S. nigrum has been traditionally used to treat various liver disorders. In a study, the extract of the fruits of S. nigrum  was found to be hepatoprotective in a rat model of CCl4-induced hepatic damage.

Problems with liver, stomach and pancreas etc can reduce the number of important enzymes that a body produce. As a result, a person may not get enough enzymes to thoroughly digest food and obtain all the nutritional value. According to Ayurveda, indigestion occurs due to imbalanced agni (digestive fire). Digestive fire is correlated to gastric juices and different enzymes at gastrointestinal level.

Ornazym is the herbal formulation that encourages the body’s own enzyme secretion by maintaining the proper functioning of enzyme secreting organs. It is a plant-based enzyme promoting formulation design to assist the digestion by balancing the imbalanced agni.

  • Ingredients such as Ajwain, Kutaki, Bhringraj and Kakmachi provide relief from flatulence, bloating and indigestion.
  • Amaltas provides relief from constipation and improves digestion.
  • Bhumiamlaki, Kutaki and Rohitak have hepatoprotective action which efficiently maintains the health of the liver.
  • Ornazym provides a complete solution for healthy functioning of stomach and liver by restoring Digestive fire and provides freedom from discomfort and promotes proper digestion of the food.
  • MALE REPRODUCTIVE HEALTH
  • SPERM ABNORMALITY
  • REVIFERT