INSORMAC-H TABLET

Each tablet contains:

Aqueous extract derived from: Mandukparni 650mg, Kushmand 350 mg, Ashwagandha 350mg,  Amla 200mg, Sarpagandha 200mg, Ustakhadus 200mg

Powders of: Jatamamsi 75mg, Ustakhadus 50mg, Sugandhbala 50mg

Mandukparni (Centella asiatica)

In ayurveda it is described under the Medhya rasayana drugs. It has adaptogen, CNS relaxant and sedative action. It reduces tension, stress, anxiety and sleeplessness due to its sedative, tranquilizing and relaxant activity.

 Kushmand (Benincasa hispida)

Kushmanda is one of the Medhya Rasayana. In some studies,extract of Benincasa hispida fruit has been demonstrated to possess nootropic, antidepressant and anxiolytic like effect, which suggests that Benincasa hispida influences various neurotransmitter systems including serotonergic system.

Ashwagandha (Withania somnifera)

It is considered as nervine tonic which is helpful in problems like anxiety, depression and insomnia etc. Research conducted at the Department of Pharmacology; University of Texas Health Science Center indicated that extracts of Ashwagandha produce GABA-like activity, owing to its anxiolytic effect.

In another study, the antistress activity of W. somnifera on cold swimming stress was evaluated and the results indicate a significant increase in the plasma corticosterone level, phagocytic index and avidity index in rats subjected to cold swimming stress. In the rats pretreated with the drug, these parameters were near control values and an increase in the total swimming time was observed W. somnifera is a potent antistressor agent in the crude form.^{Journal of Ethnopharmacology 64 (1999) 91–93}

 Amla (Emblica officinalis)

In Ayurveda, amla is well known rasayana drug and it is also known to cure insomnia. Extract of fruits of Emblica officinalis was investigated on acute anoxia stress tolerance test in Swiss mice. The results indicate that extract of Emblica officinalis has significant Adaptogenic activity against variety of biochemical and physiological perturbations.^{Int. J. of Res. in Pharmacology &Pharmacotherapeutics Vol-3(1) 2014 [72-79]}

 Sarpgandha (Rauwolfia serpentine)

Sarpagandha has Nidrajanaka Karma. Research works done on Sarpagandha shows that it is hypnotic, sedative, hypotensive, and CNS depressant in action.

A Study was conducted on 30 patients of Nidranasha (primary Insomnia). Sarpagandha tablets were prepared by giving Bhavana of Sarpagandha Moola Kashaya (root decoction) and were given to patients for the duration of one month. Highly significant improvements were observed in chief complaints like sleep initiation, maintaining sleep, early morning awakening. ^{Jour. of Ayurveda & Holistic Medicine; Volume-III, Issue-IV: 30-41.}

Ustakhadus (Lavandula stoechas)

Ustakhadus helps to diminish Kapha and Vata dosha. Results of several studies support its efficacy as a relaxant. Researchers tested the sedative properties of lavender essential oil and its main constituents, linalool and linalyl acetate.^{Lavandulastoechas L.A Guide to Medicinal Plants in North Africa, p- 171-173.}

 Jatamansi (Nardostachys jatamansi)

Jatamansi has tridosha balancing properties and exerts calming effect and improves quality of sleep and reduces sleeplessness. Studies suggest that this herb acts as a powerful antidote for sleeplessness and helps enhance the quality of sleep. In a study, the effectiveness of sedative and anxiolytic effect of N. jatamansi in compraison with diazepam. Obtained results indicated that extract of N. jatamansi gives sedative and anxiolytic effects.^{J. Med. Plants 2010, 4(36): 169-174}

Another study was undertaken to evaluate the antidepressant activity of methanolic extract of Nardostachys jatamansi. The efficacy of the extract was compared with the standard drug imipramine on normal and sleep deprived mice. Finding suggests that extract of Jatamansi has dose dependent antidepressant activity and can also be used in patients suffering from depression due to sleep disturbances. ^{Der Pharmacia Lettre, 2010, 2(5): 441-449}

 Sugandhbala (Valeriana wallichii) and Jatamansi (Nardostachys jatamansi)

A clinical study was conducted to evaluate the effect of Tagara/Sugandhbala) and Jatamansi in the management of Anidra. A total of 34 patients suffering from primary insomnia were randomly selected from Out Patient Department and In Patient Department of Manasa Roga. In this clinical study, both the groups showed good results, but Tagara group showed better results in comparison to Jatamansi group.^{Ayu. 2015 Jan-Mar; 36(1): 46–49.}

Jatamansi (Tagar) is reported to be effective in treating various sleeping disorders in human. Clinical trials on V. jatamansi have confirmed that root extract reduces sleep latency and improves sleep quality and therefore, considered useful in treating anxiety and insomnia. Many more studies have shown proven sedative effect of Tagar. ^{Phytotherapy Research. 2019;1–22.}

Sleeplessness or Insomnia is a sleep disorder in which a person has trouble falling and/or staying asleep. According to Ayurveda, insomnia or Anidra occur due to imbalance of tridosha (Vata, Pitta and Kapha). Imbalanced tridosha are the main causative factors of Anidra.

Insormac-H tablet is the herbal formulation which is effective in treating various sleeping disorders. The ingredients of Insormac-H tablets are tridoshar in nature that helps in balancing the vitiated dosha and restoration of normal sleep cycle. Insormac-H is formulated by the combination of Ayurvedic rasayana herbs which also has tranquilizer, anti-depressant and anxiolytic properties that helps to overcome insomnia caused due to stress or anxiety.

• Sarpagandha, Jatamansi, Sugandhabala are sedative in nature and CNS depressants.
• The anti-stressor agents like Ustakadhus, Ashwagandha and Amla are effective in relieving stress and restlessness and helps in providing good sleep.
• Insormac-H contains Medhya rasayana herbs like Mandukparni, Kushmanda, which will also provide strength to the brain & relieves mental fatigue.
• Insormac-H does not cause excessive sedation. Therefore, daily activities will not be hampered.